3-CARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Names and Identifiers
3-CARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Physico-chemical Properties
Molecular Formula | C10H18N2O3
|
Molar Mass | 214.26 |
Density | 1.155±0.06 g/cm3(Predicted) |
Melting Point | 117.0 to 121.0 °C |
Boling Point | 370.1±31.0 °C(Predicted) |
Flash Point | 177.613°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | Light yellow crystalline powder |
Color | White to Almost white |
pKa | 16.40±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.504 |
MDL | MFCD04116210 |
3-CARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Risk and Safety
Risk Codes | 22 - Harmful if swallowed
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
3-CARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Introduction
1-BOC-pyrrolidine-3-carboxamide is an organic compound whose chemical formula is C11H17NO3.
Nature:
1-BOC-pyrrolidine-3-formamide is a colorless to pale yellow liquid with a special ammonia odor and pungent taste. It has a low boiling point and a high flash point.
Use:
1-BOC-pyrrolidine-3-carboxamide is an important intermediate in organic synthesis. It is commonly used in drug synthesis as a protecting group to protect receptive groups from undesirable reactions under reaction conditions. In addition, it can also be used for the synthesis of hormones, enzyme inhibitors, peptides and anti-cancer drugs.
Preparation Method:
1-BOC-pyrrolidine-3-carboxamide can be obtained by reacting pyrrolidine with Boc-acid chloride. The reaction is usually carried out at room temperature, and the product can be obtained by extraction and purification steps.
Safety Information:
1-BOC-pyrrolidine-3-formamide needs to pay attention to the following aspects of safety during use and storage:
-Inhalation or exposure to the compound may cause irritation and injury, so wear appropriate protective equipment, including glasses, gloves and lab clothes.
-Avoid direct exposure to flame or high temperature because it has a lower flash point.
-Store in a dry, well-ventilated place and separate from other chemicals.
-Dispose of surplus material and waste properly and follow local chemical waste disposal regulations.
Last Update:2024-04-09 20:49:11